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Project Case Study | Laboratory Animal Facility Chinese Academy of Sciences Shanghai Laboratory Animal Facility Project Case Study: Cleanroom Envelope and Environmental Control Interfaces A Wonclean project case for a Shanghai Chinese Academy of Sciences laboratory animal facility, focusing on cleanroom wall panels, cleanroom doors, controlled corridors, equipment interfaces and visible environmental monitoring. cleanroom wall system cleanroom panels cleanroom doors pass box Laboratory animal facilities are not ordinary cleanrooms. They must support animal welfare, research reliability, operator safety, controlled personnel flow, controlled material transfer and daily sanitation. In this Shanghai Chinese Academy of Sciences animal facility project, the cleanroom envelope was treated as an integrated engineering system rather than a collection of isolated panels and doors. Project photo. Controlled animal-facility corridor with cleanroom wall panels, cleanroom doors, viewing windows, return air grille and ceiling service interfaces. Project Snapshot A Multi-Discipline Animal Facility Package The reviewed project folder identifies a Shanghai Chinese Academy of Sciences project with laboratory animal room drawings, South Building 2 animal-room documentation, wall-panel manufacturing data, cleanroom door data and a broader CAD package covering architecture, process, electrical, power/HVAC, water supply and drainage, fire protection and information/BA systems. Confirmed project facts from reviewed local files and site photos. Item Confirmed detail Engineering value Project type Laboratory animal facility / animal room project in Shanghai. Requires cleanable rooms, controlled access, coordinated utilities and environmental control. Building area in project files South Building 2 animal-room drawings; 7F-9F animal-room related wall-panel documentation. Shows a multi-floor project scope rather than a single isolated room. Wall system 50 mm handmade purification panels with 0.5 + 0.5 mm custom white-gray steel sheet noted in the reviewed panel schedule. Supports cleanable walls, coordinated panel sizes and repeatable installation in controlled animal areas. Access control Cleanroom doors, observation windows, air shower / personnel entry interfaces and door schedules are present in project files or site photos. Helps separate clean corridors, rooms, support spaces and transfer paths. Environmental monitoring Site photo shows live monitoring fields for pressure differential, air changes, supply/exhaust airflow, temperature and humidity. Supports operational visibility for room status and HVAC balancing. Cleanroom Envelope Why Animal Facilities Need More Than Smooth Walls Animal-room wall panels must tolerate repeated wiping, disinfection, impact from carts and cage equipment, and frequent traffic at doors and corners. The reviewed panel schedule for this project lists 50 mm handmade purification panels with 0.5 + 0.5 mm color steel sheet construction. The ...
Project Case Study | Malaysia Modular Cleanroom Genetek Malaysia Cleanroom Project Case Study: Modular Envelope, Air Shower, H13 HEPA Terminals and DX AHU Integration A Malaysia cleanroom project where Wonclean coordinated the modular cleanroom envelope, personnel air showers, flush vision windows, H13 terminal HEPA outlets and direct-expansion AHU requirements into one buildable project package. modular cleanroom cleanroom wall system air shower room cleanroom doors For a cleanroom project outside the supplier's home market, the real challenge is not only producing panels or shipping equipment. The project must connect drawings, fabricated wall modules, doors, air showers, terminal filtration, AHU capacity and site installation logic before the cleanroom reaches the customer facility. The Genetek Malaysia project is a useful example of how Wonclean turns those separate workstreams into a coordinated cleanroom package. Project photo. Front view of the Genetek Malaysia modular cleanroom envelope during workshop assembly and inspection. Project Snapshot What Was Coordinated for the Malaysia Cleanroom The available project package includes structural drawings, HVAC drawings, electrical drawings, a 3D model file, AHU equipment information and manufacturing order data. That matters because a cleanroom envelope is only reliable when the wall panels, openings, duct connections, electrical routes and access equipment are checked as one system. Project facts confirmed from the reviewed Genetek Malaysia manufacturing order and project file structure. Item Confirmed project detail Why it matters Project location Malaysia Supports export coordination, packaging, drawing control and site installation planning. Cleanroom envelope Modular wall system with integrated doors, windows and service interfaces. Reduces uncontrolled field cutting and keeps openings aligned with the drawings. Vision windows 3 sets, 980 x 1000 mm, double-layer glass, 5 mm glass, flush frame with desiccant. Improves visibility while reducing ledges and moisture risk inside glazing assemblies. Personnel air showers One three-door unit and one two-door unit, each 1200 x 900 x 2300 mm, stainless steel, single-side blowing. Controls gowning-area entry and helps reduce loose particles carried by personnel flow. Terminal HEPA outlets 6 sets, H13 filter specification, 500 m3/h per outlet, 200 x 200 mm connection. Connects filtration capacity with HVAC layout and room air distribution planning. AHU system TICA direct-expansion AHU, 2500 m3/h, 650 Pa static pressure, 19-25 C temperature control range. Shows that air volume, static pressure and temperature control were handled as project-level requirements. Modular Envelope A Cleanroom Shell Built Around Interfaces, Not Only Panels In a modular cleanroom project, the wall panel surface is only one part of performance. The harder details are at the edges: door frames, observation windows, ceiling transitions, duct penetrations, electrical service ro...
Technical Blog | Sterile Compounding Cleanrooms Modular Pharmacy Clean Rooms for Sterile Compounding: USP 797/800 Zoning, Negative-Pressure Rooms and Panel Selection Modular pharmacy clean rooms must connect sterile compounding workflow with pressure control, HEPA supply, cleanable panels, pass-through transfer and the separation logic required for hazardous and non-hazardous preparations. modular cleanroom cleanroom wall panels cleanroom doors pass box A pharmacy cleanroom is not simply a small laboratory with HEPA filters. It is a controlled compounding environment where room zoning, personnel flow, material transfer, pressure relationships and surface cleanability all affect contamination control. A modular approach can shorten construction time, but it does not reduce the need for regulatory planning. Real project photo. Pharmacy cleanroom zoning should separate support spaces, buffer rooms and controlled compounding areas with clear pressure relationships. USP Zoning Logic Separate Sterile Workflow Before Selecting Panels USP General Chapter <797> addresses sterile compounding standards intended to reduce risks such as contamination and infection. For facility planning, the key takeaway is that workflow and environmental control must be defined before the wall system is ordered. The project should map receiving, gowning, hand hygiene, staging, compounding, waste, cleaning and sample transfer. A modular pharmacy clean room can then be broken into cleanable room modules with doors, pass-throughs, HEPA diffusers and pressure monitoring already coordinated. For hazardous drug handling, the design must not assume that a positive-pressure sterile suite is enough. Containment and worker protection must be reviewed separately from sterile product protection. Pressure Cascade Negative-Pressure Rooms Require a Containment Mindset USP General Chapter <800> addresses hazardous drugs and aims to minimize exposure risk to healthcare personnel, patients and the environment. In practice, this means that hazardous compounding rooms need careful pressure relationships, exhaust strategy, access control and cleaning procedures. Modular pharmacy cleanroom planning matrix. Zone Primary concern Cleanroom design response Ante or support area Personnel transition and material staging. Cleanable panels, controlled doors and visible pressure monitoring. Sterile buffer room Product protection and HEPA-supplied clean air. Coordinated ceiling diffusers, sealed joints and low-shedding surfaces. Hazardous drug room Containment and exposure reduction. Negative-pressure layout, exhaust planning and dedicated transfer route. Pass-through interface Material transfer without uncontrolled door opening. Interlocked pass box, cleanable frames and documented cleaning access. Real project photo. Cleanroom doors, windows and ceiling supply points should be coordinated with the pressure cascade and compounding workflow. Panel Selection Cleanable Wall Panels Are Part of the...
Technical Blog | Semiconductor Panel Engineering Cleanroom Panel Deflection Control for Semiconductor Fabs: Aluminum Honeycomb, Rockwool and Reinforced Frames In semiconductor fabs, panel deflection is not only a structural detail. Long-span cleanroom walls, walkable ceilings, door openings and equipment airflow can all turn small movement into seal stress, particle traps and qualification risk. cleanroom wall system cleanroom sandwich panel ceiling system modular cleanroom Cleanroom panel deflection control starts with a simple question: what movement can the room tolerate without losing surface integrity, pressure stability or cleanability? The answer depends on panel core, face skin, span, support spacing, ceiling loads, door and window openings, equipment vibration and the way the wall connects to the floor and ceiling. Real product photo. Aluminum honeycomb cleanroom panels are often selected where stiffness-to-weight ratio and dimensional stability are important. Deflection Risk Why Panel Movement Matters in Semiconductor Cleanrooms In a normal room, slight panel movement may only be an appearance issue. In a semiconductor cleanroom, deflection can affect joint sealant, door frame alignment, return air leakage, ceiling gasket compression and the long-term cleanability of wall-to-ceiling junctions. A panel that bows under load can also create ledges where particles settle. The design team should review panel span, core material, face sheet thickness, reinforcement, support method and service openings together. Long wall runs, tall partitions, walkable ceiling zones and heavy access panels need more attention than small enclosed rooms. ISO 14644-4:2022 frames cleanroom creation from requirements through design, construction and start-up. For panel deflection, that means structural and architectural requirements should be defined before panels are fabricated. Material Selection Aluminum Honeycomb Panel vs. Rockwool Sandwich Panel An aluminum honeycomb panel can provide high stiffness with lower weight, making it useful for large ceiling modules, tall partitions or cleanroom areas where flatness is critical. A rockwool sandwich panel is often considered when fire behavior, acoustic performance, thermal insulation and cost balance are important. Neither material is automatically better in every location; each must be matched to span, support and cleanroom risk. Panel deflection control logic for semiconductor cleanroom walls and ceilings. Panel strategy Best-fit use case Engineering check Aluminum honeycomb panel Long spans, lightweight ceiling panels and flatness-sensitive walls. Support spacing, edge closure, face sheet thickness and opening reinforcement. Rockwool sandwich panel Fire-rated or acoustic partitions where insulation is also required. Core density, joint compression, panel length and frame support. Reinforced frame Door openings, windows, pass-throughs and service penetrations. Load transfer path, anchorage, corrosion resistance a...
Technical Analysis | Semiconductor Cleanroom Wall Panels Cleanroom Wall Panel Detailing for Semiconductor Fabs: Sealants, Penetrations, Windows and Particle Leakage Control Cleanroom wall panels are pressure boundaries, service interfaces and cleaning surfaces at the same time. In semiconductor fabs, the detailing around sealants, utility penetrations, vision windows and door frames can decide whether a cleanroom wall system remains stable after installation. cleanroom wall panels clean room wall panels cleanroom door interface semiconductor cleanroom JointsKeep panel seams flush, sealed and inspectable. OpeningsDetail sleeves, gaskets and service cut-outs. WindowsAvoid ledges around vision panels and frames. LeakageProtect pressure cascade and particle control. A semiconductor cleanroom wall system should not be judged only by the panel core. The final performance depends on details: sealant lines, panel alignment, door interfaces, window frames, utility penetrations, return-air openings and how each joint survives cleaning and pressure cycling. Good detailing reduces rework and helps the cleanroom hold its classification after real production begins. Real cleanroom photo. Flush window, wall and door interfaces show the detailing required to reduce ledges and leakage paths. Joint Detailing Panel Joints Should Be Designed as Cleanable Pressure Boundaries Panel joints are small details with large consequences. A poor joint creates a ledge for dust, a weak point for pressure leakage and a maintenance problem after repeated wiping. A good joint has controlled alignment, compatible sealant, enough backing support and an inspection method that can be repeated during installation and maintenance. ISO 14644-4 addresses cleanroom design, construction and start-up. For wall panels, this means details must be connected to the cleanroom requirement, not selected as decorative finishes. The joint design should support cleanability, air leakage control, durability and future panel replacement. In semiconductor fabs, even support spaces can contain sensitive metrology, packaging or precision assembly functions. Wall panel detailing should therefore be consistent across the cleanroom envelope, not improvised room by room. Sealants and Materials Sealant Choice Must Match Movement, Cleaning and Process Risk Sealant is often treated as a small site material, but it is part of the cleanroom wall system. It should tolerate panel movement, cleaning agents, temperature and humidity range, and the required maintenance interval. The detail should define surface preparation, bead geometry, curing conditions, inspection criteria and repair method. Detailing priorities for semiconductor cleanroom wall panels. Detail Common failure mode Specification response Vertical panel joint Cracking, ledge formation or air leakage. Define backing, sealant type, bead profile and inspection criteria. Floor-to-wall transition Dirt trap or cleaning residue at the base. Use compatible cove...
Technical Analysis | Semiconductor Tool-Install Cleanrooms Tool-Install Ready Modular Cleanrooms for Semiconductor Fabs: Utility Chases, Panel Penetrations and Start-Up Risk A tool-install ready modular cleanroom is planned around the moment when process equipment enters the fab. Wall panels, service penetrations, utility chases, FFU ceiling grids and inspection records must be coordinated before move-in, or the cleanroom can look complete while still creating start-up risk. modular cleanroom modular clean room panels FFU ceiling grid fan filter unit ToolsReserve footprints, clearances and move-in paths. UtilitiesCoordinate gas, exhaust, drains, power and data routes. EnvelopeDetail penetrations without losing pressure stability. Start-UpPrepare evidence for airflow, pressure and filter tests. The difference between a generic modular cleanroom and a tool-install ready modular cleanroom is not the panel material alone. It is the coordination discipline. Semiconductor tools often arrive with tight hook-up requirements, sensitive airflow zones, heat loads, exhaust points, vibration concerns and service access needs. If these interfaces are treated as late site work, the cleanroom envelope becomes a source of drilling, rework and contamination risk. Real project photo. Factory-built modular cleanroom unit showing external access and prefabricated enclosure before cleanroom fit-out. Tool Footprint Planning Freeze the Tool Matrix Before Freezing the Panel Grid For semiconductor projects, the cleanroom panel grid should be checked against process equipment, metrology benches, transfer carts, maintenance access and future tool positions. A module grid that looks efficient on a floor plan can become expensive if a later utility sleeve lands behind a tool, if a door swing blocks a maintenance route, or if a panel joint conflicts with a high-use service penetration. ISO 14644-4 frames cleanroom creation around requirements, design, construction and start-up. In a tool-install cleanroom, this means the user requirement specification should include tool clearances, hook-up zones, utilities, exhaust, pressure map, air return paths, ceiling service access and documentation expectations before the modular package is released. Wonclean modular clean room panels can support fast deployment, but the fastest project is usually the one that avoids late cutting. Each penetration should have a reason, a location, a sealing method and an inspection step. Utility Chases Use Utility Chases to Keep Service Work Out of the Clean Zone A utility chase can separate frequent service activity from the cleaner process zone. It can carry electrical distribution, data, gases, vacuum, exhaust, chilled water, drains, monitoring cables or cleanroom controls depending on the process. The goal is not to hide services. The goal is to keep them accessible without repeatedly opening the cleanroom envelope. Tool-install coordination logic for semiconductor modular cleanrooms. Interface Risk...
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